ポピュラーベクター Rat Bdnf

Enables neurotrophin TRKB receptor binding activity. Involved in several processes, including behavioral response to cocaine; cellular response to norepinephrine stimulus; and regulation of neuronal synaptic plasticity. Acts upstream of or within positive regulation of DNA-binding transcription factor activity; positive regulation of glucocorticoid receptor signaling pathway; and positive regulation of peptidyl-serine phosphorylation. Located in several cellular components, including mitochondrial crista; perikaryon; and synaptic vesicle. Used to study Alzheimer\'s disease; cystitis; eye disease (multiple); neuropathy (multiple); and status epilepticus. Biomarker of several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; hypertensive encephalopathy; middle cerebral artery infarction; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including cognitive disorder (multiple); congenital central hypoventilation syndrome; neurodegenerative disease (multiple); obstructive sleep apnea; and status epilepticus. Orthologous to human BDNF (brain derived neurotrophic factor). [provided by Alliance of Genome Resources, Apr 2022]

NM_001270630.1; NM_001270631.1; NM_001270632.1; NM_001270633.1; NM_001270634.1; NM_001270635.1; NM_001270636.1; NM_001270637.1; NM_001270638.1; NM_012513.4

NP_001257559.1; NP_001257560.1; NP_001257561.1; NP_001257562.1; NP_001257563.1; NP_001257564.1; NP_001257565.1; NP_001257566.1; NP_001257567.1; NP_036645.2