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Direct conversion of urine-derived cells into functional motor neuron-like cells by defined transcription factors
Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance
Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health
Lactylated Apolipoprotein C‐II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis
A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells
Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation
MMP12 disrupts epithelial barrier integrity in oral lichen planus by degrading fibronectin
The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution
Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resources
Mammalian ubiquitous promoter isolated from proximal regulatory region of bovine MSTN gene
Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia
Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance
TULIPs decorate the three-dimensional genome of PFA ependymoma
A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids
Discovery and engineering of ChCas12b for precise genome editing
An atlas of the aging mouse proteome reveals the features of age-related post-transcriptional dysregulation
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy
A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings
Temporal variation in p38-mediated regulation of DUX4 in facioscapulohumeral muscular dystrophy
Development and evaluation of vaccination strategies for addressing the continuous evolution SARS-CoV-2 based on recombinant trimeric protein technology: Potential for cross-neutralizing activity and broad coronavirus response
Successful delivery of CRISPR-Cas9 with a baculovirus vector for insect brain targets
Identification of a novel myosin antigen activating CD8+ T cells in C57BL/6 mice