VectorBuilderを使って自分のベクターをデザインすることができます。以下によく使われるコンポーネントの解説があります。
Heavy Chain Constant Region (CH)
| 名前 | 詳細 | アプリケーションノート | レファレンス | シークエンス |
|---|---|---|---|---|
| hlgG1-CH | Human IgG1 heavy chain constant region | Encodes the constant region of the human IgG1 heavy chain. | Nucleic Acids Res. 10:4071 (1982); J Virol. 93:e02270 (2019); | View |
| mlgG1-CH | Mouse IgG1 heavy chain constant region | Encodes the constant region of the mouse IgG1 heavy chain. | Proc Natl Acad Sci U S A. 1980 Apr; 77(4): 2143–2147. | View |
| mlgG2a-CH | Mouse IgG2a heavy chain constant region | Encodes the constant region of the mouse IgG2a heavy chain. | Proc Natl Acad Sci U S A. 78: 4495 (1981) | View |
| mlgG2b-CH | Mouse IgG2b heavy chain constant region | Encodes the constant region of the mouse IgG2b heavy chain. | Proc Natl Acad Sci U S A. 78: 4495 (1981) | View |
Light Chain Constant Region (CL)
| 名前 | 詳細 | アプリケーションノート | レファレンス | シークエンス |
|---|---|---|---|---|
| hIgκ-CL | Human immunoglobulin kappa light chain constant region | Encodes the constant region of the human kappa light chain. | Cell. 22(1 Pt 1):197 (1980); Appl Microbiol Biotechnol. 102:5953 (2018); J Virol. 93: e02270 (2019) | View |
| hIgλ2-CL | Human immunoglobulin lambda 2 light chain constant region | Encodes the constant region of the human lambda 2 light chain. | Immunogenetics. 25:63 (1987); J Immunol. 169:271 (2002); Acta Pharm Sin B. 9:960 (2019) | View |
| mIgκ-CL | Mouse immunoglobulin kappa light chain constant region | Encodes the constant region of the mouse kappa light chain. | Cell. 22(1 Pt 1):197 (1980); Curr Biol. 25:R820 (2015) | View |
| mIgλ1-CL | Mouse immunoglobulin lambda 1 light chain constant region | Encodes the constant region of the mouse lambda 1 light chain. | Nature. 298:380 (1982) | View |
| mIgλ2-CL | Mouse immunoglobulin lambda 2 light chain constant region | Encodes the constant region of the mouse lambda 2 light chain. | Nucleic Acids Res. 10:3831 (1982) | View |