要約
This record represents the promoter and related 5\' regulatory region of the integrin binding sialoprotein gene, also known as BSP. The proximal promoter is highly conserved in mammals and is bound by runt related transcription factor 2, cAMP responsive element binding protein 1, and AP-1 family transcription factors. Activity of this promoter is induced by parathyroid hormone, platelet-derived growth factor, fibroblast growth factor 2, calcium hydroxide, interleukin 11, and melatonin, among other factors. This region includes an L1 retrotransposon-derived sequence that represses promoter activity. [provided by RefSeq, May 2017]
